Acyclovir is acyclic purine nucleoside
analogue active against herpes simplex virus, varicella zoster, Epstein-Barr
virus and cytomegalovirus. In the cell, undergo phosphorylation acyclovir
acyclovir triphosphate into an active form that inhibit the herpes simplex
virus DNA polymerase and viral DNA replication, thereby preventing viral DNA
synthesis without affecting normal cell processes.
Acyclovir Pharmacology
Acyclovir is an antiviral agent highly active in vitro against herpes simplex virus (HSV) types I and II, and varicella zoster virus. Upon entry into the infected cell, the phosphorylated form of the active compound Acyclovir Acyclovir trifosfate. The initial phase of the process depends on the enzyme thymidine kinase viral-coded. Acyclovir trifosfate act as inhibitors and as a false substrate for the herpes-specified DNA polymerase which prevents viral DNA synthesis without affecting normal cellular processes.
Treatment of herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes / recurrent, herpes zoster (shingles / shingles / shingles). Preventing recurrence of herpes simplex infections in patients with strong immune systems. Preventing herpes simplex infection in patients with poor immune systems.
Another acyclovir pharmacology is a treatment of herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes / recurrent, herpes zoster (shingles / shingles / shingles); preventing recurrence of herpes simplex infections in patients with strong immune systems; preventing herpes simplex infection in patients with poor immune systems.
Acyclovir Indication
Acyclovir indication such as treatment of herpes simplex virus on the skin and mucus membranes, including initial and recurrent genital herpes; treatment of herpes zoster and varicella infections; treatment of infections caused by the herpes simplex of the skin and mucous membranes including initial and recurrent genital herpes, herpes simplex infection prevention in immuno-compromised patients; treatment of herpes zoster infection.
Acyclovir Pharmacology
Acyclovir is an antiviral agent highly active in vitro against herpes simplex virus (HSV) types I and II, and varicella zoster virus. Upon entry into the infected cell, the phosphorylated form of the active compound Acyclovir Acyclovir trifosfate. The initial phase of the process depends on the enzyme thymidine kinase viral-coded. Acyclovir trifosfate act as inhibitors and as a false substrate for the herpes-specified DNA polymerase which prevents viral DNA synthesis without affecting normal cellular processes.
Treatment of herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes / recurrent, herpes zoster (shingles / shingles / shingles). Preventing recurrence of herpes simplex infections in patients with strong immune systems. Preventing herpes simplex infection in patients with poor immune systems.
Another acyclovir pharmacology is a treatment of herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes / recurrent, herpes zoster (shingles / shingles / shingles); preventing recurrence of herpes simplex infections in patients with strong immune systems; preventing herpes simplex infection in patients with poor immune systems.
Acyclovir Indication
Acyclovir indication such as treatment of herpes simplex virus on the skin and mucus membranes, including initial and recurrent genital herpes; treatment of herpes zoster and varicella infections; treatment of infections caused by the herpes simplex of the skin and mucous membranes including initial and recurrent genital herpes, herpes simplex infection prevention in immuno-compromised patients; treatment of herpes zoster infection.
Acyclovir
an antiviral agent with activity against herpesvirus types 1 and 2 and varicella zoster virus. Acyclovir is converted by a herpesvirus enzymeinto a molecule (acyclovir triphosphate) that inhibits the synthesis of deoxyribonucleic acid (DNA) molecules in the virally infected cells,thereby inhibiting viral replication.
indications It is prescribed topically in an ointment for the treatment of herpes simplex lesions (cold sores) and both orally andsystemically (oral and IV) in other types of herpes infections, including genital herpes, herpes encephalitis, chickenpo
(varicellazoster), and shingles (herpes zoster).
contraindication Known sensitivity to this drug prohibits its use.
adverse effects After topical use, irritation or pruritus may occur; after systemic use, diaphoresis, headache, and nausea may occur.When it is administered intravenously in the treatment of immunosuppressed patients, there may be pain at the site of the injection,and 1% to 10% of such patients experience acute renal failure.
Acyclovir
A nucleoside analogue used to manage viral infections in patients with bone marrow transplants, chemotherapy-induced oracquired immunosuppression—e.g., AIDS.
Indications HSV-1, HSV-2, HVZ, and CMV. Acyclovir is considered safe for paediatric chickenpox (varicellazoster) if begun in the first 24hours of rash, although it is unclear if it reduces the rare serious complications of chickenpox or is more effective than vidarabine in reducingviral shedding by HSV-infected infants.
Adverse effects Upset stomach, headache, nausea; hair loss with chronic use.
Indications HSV-1, HSV-2, HVZ, and CMV. Acyclovir is considered safe for paediatric chickenpox (varicellazoster) if begun in the first 24hours of rash, although it is unclear if it reduces the rare serious complications of chickenpox or is more effective than vidarabine in reducingviral shedding by HSV-infected infants.
Adverse effects Upset stomach, headache, nausea; hair loss with chronic use.
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